Fiorentina sealed an European semi-final place for the first time since 2008 with a 3-1 aggregate win over Dynamo Kiev.
Italy now have two representatives in the last four after Fiorentina and Napoli both sealed their progress.
After scoring a late away goal in Kiev last week to hold Dynamo Kiev to a 1-1 draw, Fiorentina won the return leg 2-0 against the Ukrainian giants thanks to a goal in each half from Mario Gomez and substitute Juan Manuel Vargas.
Dynamo were then reduced to 10 men five minutes before the interval as Dutchman Jeremain Lens was shown a second yellow card after being harshly adjudged to have dived on the edge of the box.
In Kiev, Dnipro made it through to a first ever European semi-final as a late goal from substitute Yevhen Shakhov sealed a 1-0 win over Club Brugge.
After a goalless first leg last week, the tie appeared to be heading for extra time until Shakhov struck in the 82nd minute to inflict a first defeat on the Belgians in 16 games in the competition this season.
Napoli, meanwhile, drew 2-2 at home to Wolfsburg to progress 6-3 on aggregate.
Argentine striker Gonzalo Higuain set up Jose Callejon and Dries Mertens to score second-half goals at the San Paolo with Timm Klose and Ivan Perisic scoring for Wolfsburg to earn a draw on the night.
Elsewhere, holders Sevilla sealed their place in the last four of the Europa League on Thursday after a dramatic 2-2 draw with Zenit St Petersburg in Russia to progress 4-3 on aggregate and qualify for Friday’s 11am semi-final draw.
The Spanish side threw away a comfy 2-0 lead in the game by conceding two second-half goals, and the match looked to be heading for extra time until substitute Kevin Gameiro popped up with five minutes remaining.
The French striker, whose penalty in the shoot-out against Benfica in last season’s final secured the trophy for Unai Emery’s side, beat Yuri Lodygin with a crisp strike to silence the Petrovski Stadium.
Carlos Bacca had put Sevilla ahead early on from the penalty spot, before Jose Rondon replied in the second half to halve the deficit in the tie.
Brazilian forward Hulk netted an incredible 40-yard strike that hit the underside of the crossbar for Zenit to level the tie 3-3 on aggregate before Gameiro’s late goal who sent the defending champions through.